Description
| Product Name: | S100A12/CGRP Monoclonal Antibody |
| Product Code: | CAB23912 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61785 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F transfected by S100A12/CGRP |
| Cellular Location: | Cell membrane, Cytoplasm, Peripheral membrane protein, Secreted, cytoskeleton |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12/CGRP (NP_005612.1). |
| Sequence: | MTKLE EHLEG IVNIF HQYSV RKGHF DTLSK GELKQ LLTKE LANTI KNIKD KAVID EIFQG LDANQ DEQVD FQEFI SLVAI ALKAA HYHTH KE |
| Synonyms: | p6, CAGC, CGRP, MRP6, CAAF1, MRP-6, ENRAGE |
| Calculated MW: | 10kDa |
| Observed MW: | 11kDa |
