Description
Product Name: | S100A11 Monoclonal Antibody |
Product Code: | CAB22563 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57872 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, Jurkat(negative) |
Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1). |
Sequence: | MAKIS SPTET ERCIE SLIAV FQKYA GKDGY NYTLS KTEFL SFMNT ELAAF TKNQK DPGVL DRMMK KLDTN SDGQL DFSEF LNLIG GLAMA CHDSF LKAVP SQKRT |
Synonyms: | MLN70, S100C, HEL-S-43 |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |