Description
Product Name: | S100/S100A1 Monoclonal Antibody |
Product Code: | CAB23494 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58770 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | SK-MEL-28, Mouse heart, HepG2, C2C12, Rat kidney |
Cellular Location: | Cytoplasm |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Immunogen: | Recombinant protein of human S100/S100A1. |
Sequence: | Email for sequence |
Synonyms: | S100, S100A, S100-alpha |
Calculated MW: | 11kDa |
Observed MW: | 12kDa |