S Antibody (PACO34410)

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SKU:
PACO34410
Product Type:
Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:S Antibody (PACO34410)
Antibody SKU:PACO34410
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Bovine coronavirus
Immunogen:Recombinant Bovine coronavirus Spike glycoprotein protein (326-540AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid, containing proteins, initiating the infection.By similarity S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes (By similarity).
Synonyms:Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1 (90B); Spike protein S2 (90A)], S
UniProt Protein Function:S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.
UniProt Protein Details:
NCBI Summary:
UniProt Code:P25194
NCBI GenInfo Identifier:138174
NCBI Gene ID:
NCBI Accession:P25194.1
UniProt Secondary Accession:P25194
UniProt Related Accession:P25194
Molecular Weight:
NCBI Full Name:Spike glycoprotein
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Spike glycoprotein
UniProt Synonym Protein Names:E2; Peplomer protein
Protein Family:
UniProt Gene Name:S  
UniProt Entry Name:SPIKE_CVBV
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