RYR1 Polyclonal Antibody
- SKU:
- CAB23056
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | RYR1 Polyclonal Antibody |
| Product Code: | CAB23056 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse skeletal muscle |
This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human RYR1 (NP_000531.2). |
| Sequence: | KFLPP PGYAP CHEAV LPRER LHLEP IKEYR REGPR GPHLV GPSRC LSHTD FVPCP VDTVQ IVLPP HLERI REKLA ENIHE LWALT RIEQG WTYGP VRDDN K |
| Synonyms: | CCO, KDS, MHS, RYR, MHS1, RYDR, SKRR, RYR-1, CMYP1A, CMYP1B, PPP1R137 |
| Calculated MW: | 565kDa |
| Observed MW: | 565kDa |
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