Description
Antibody Name: | ruvC Antibody (PACO34922) |
Antibody SKU: | PACO34922 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Escherichia coli |
Immunogen: | Recombinant Escherichia coli Crossover junction endodeoxyribonuclease RuvC protein (2-173AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. |
Synonyms: | Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) (Holliday junction nuclease RuvC) (Holliday junction resolvase RuvC), ruvC |
UniProt Protein Function: | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. |
UniProt Protein Details: | |
NCBI Summary: | RuvABC is an enzymatic complex which functions in recombination pathways to by binding to recombinational junctions and catalyzing strand cleavage and branch migration. [More information is available at EcoCyc: EG10925]. |
UniProt Code: | P0A814 |
NCBI GenInfo Identifier: | 16129816 |
NCBI Gene ID: | 946378 |
NCBI Accession: | NP_416377.1 |
UniProt Secondary Accession: | P0A814,P24239 |
UniProt Related Accession: | P0A814 |
Molecular Weight: | 34.62kD |
NCBI Full Name: | component of RuvABC resolvasome, endonuclease |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | ruvC |
NCBI Official Synonym Symbols: | ECK1864; JW1852 |
NCBI Protein Information: | component of RuvABC resolvasome, endonuclease |
UniProt Protein Name: | Crossover junction endodeoxyribonuclease RuvC |
UniProt Synonym Protein Names: | Holliday junction nuclease RuvC; Holliday junction resolvase RuvC |
Protein Family: | Crossover junction endodeoxyribonuclease |
UniProt Gene Name: | ruvC |
UniProt Entry Name: |