RTN4IP1 Antibody (PACO39510)
- SKU:
- PACO39510
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RTN4IP1 Antibody (PACO39510) |
| Antibody SKU: | PACO39510 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Reticulon-4-interacting protein 1, mitochondrial protein (41-396AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human appendix tissue using PACO39510 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO39510 at dilution of 1:100. |
| Background: | Appears to be a potent inhibitor of regeneration following spinal cord injury. |
| Synonyms: | Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein), RTN4IP1, NIMP |
| UniProt Protein Function: | RTN4IP1: Appears to be a potent inhibitor of regeneration following spinal cord injury. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: MitochondrialChromosomal Location of Human Ortholog: 6q21 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q8WWV3 |
| NCBI GenInfo Identifier: | 76789669 |
| NCBI Gene ID: | 84816 |
| NCBI Accession: | Q8WWV3.2 |
| UniProt Secondary Accession: | Q8WWV3,Q8N9B3, Q8WZ66, Q9BRA4 |
| UniProt Related Accession: | Q8WWV3 |
| Molecular Weight: | 24,936 Da |
| NCBI Full Name: | Reticulon-4-interacting protein 1, mitochondrial |
| NCBI Synonym Full Names: | reticulon 4 interacting protein 1 |
| NCBI Official Symbol: | RTN4IP1 |
| NCBI Official Synonym Symbols: | NIMP; OPA10 |
| NCBI Protein Information: | reticulon-4-interacting protein 1, mitochondrial |
| UniProt Protein Name: | Reticulon-4-interacting protein 1, mitochondrial |
| UniProt Synonym Protein Names: | NOGO-interacting mitochondrial protein |
| Protein Family: | Reticulon-4-interacting protein |
| UniProt Gene Name: | RTN4IP1 |
| UniProt Entry Name: | RT4I1_HUMAN |
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