RTKN2 Antibody (PACO37682)
- SKU:
- PACO37682
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RTKN2 Antibody (PACO37682) |
| Antibody SKU: | PACO37682 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Rhotekin-2 protein (1-163AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO37682 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO37682 at dilution of 1:100. |
| Background: | May play an important role in lymphopoiesis. |
| Synonyms: | Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1), RTKN2, PLEKHK1 |
| UniProt Protein Function: | RTKN2: a Rho-GTPase effector protein with a PH domain. Expressed in CD4+ T-cells and bone marrow-derived B-cells. Gene expression was increased in quiescent T-cells and negligible in activated proliferating cells. Expression was absent in myeloid leukaemias, low in most B-cell malignancies and CD8+ T-cell malignancies, but very high in double positive T-lymphoblastic lymphoma. Three alternatively spliced variants have been reported in human samples.Protein type: Unknown functionChromosomal Location of Human Ortholog: 10q21.2Cellular Component: plasma membraneBiological Process: positive regulation of cell proliferation; hemopoiesis; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IZC4 |
| NCBI GenInfo Identifier: | 26190614 |
| NCBI Gene ID: | 219790 |
| NCBI Accession: | NP_660350.2 |
| UniProt Secondary Accession: | Q8IZC4,Q3ZCR1, Q68DZ6, Q8N8K1, Q8TAV2 |
| UniProt Related Accession: | Q8IZC4 |
| Molecular Weight: | 69,304 Da |
| NCBI Full Name: | rhotekin-2 |
| NCBI Synonym Full Names: | rhotekin 2 |
| NCBI Official Symbol: | RTKN2 |
| NCBI Official Synonym Symbols: | PLEKHK1; bA531F24.1 |
| NCBI Protein Information: | rhotekin-2; PH domain-containing family K member 1; pleckstrin homology domain-containing family K member 1; pleckstrin homology domain containing, family K member 1 |
| UniProt Protein Name: | Rhotekin-2 |
| UniProt Synonym Protein Names: | Pleckstrin homology domain-containing family K member 1; PH domain-containing family K member 1 |
| Protein Family: | Rhotekin |
| UniProt Gene Name: | RTKN2 |
| UniProt Entry Name: | RTKN2_HUMAN |
| Antibodies |
| RTKN2 Antibody (PACO11978) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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