Name: RPL12 Antibody (PACO49966)
SKU: PACO49966
Availability: OutOfStock

Antibody Name:	RPL12 Antibody (PACO49966)
Antibody SKU:	PACO49966
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human 60S ribosomal protein L12 protein (1-99AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunohistochemistry of paraffin-embedded human liver tissue using PACO49966 at dilution of 1:100.

Background:	Binds directly to 26S ribosomal RNA.
Synonyms:	60S ribosomal protein L12 (Large ribosomal subunit protein uL11), RPL12

UniProt Protein Function:	RPL12: a ribosomal protein of the L11P family. Located in the cytoplasm. Binds directly to the 26S rRNA. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit. Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: 9q34Cellular Component: cytosol; focal adhesion; membraneMolecular Function: protein binding; rRNA binding; structural constituent of ribosomeBiological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; ribosomal large subunit assembly and maintenance; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription
UniProt Protein Details:
NCBI Summary:	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:	P30050
NCBI GenInfo Identifier:	266921
NCBI Gene ID:	6136
NCBI Accession:	P30050.1
UniProt Secondary Accession:	P30050,Q5VVV2, Q6PB27
UniProt Related Accession:	P30050
Molecular Weight:	14,199 Da
NCBI Full Name:	60S ribosomal protein L12
NCBI Synonym Full Names:	ribosomal protein L12
NCBI Official Symbol:	RPL12
NCBI Official Synonym Symbols:	L12
NCBI Protein Information:	60S ribosomal protein L12
UniProt Protein Name:	60S ribosomal protein L12
UniProt Synonym Protein Names:
Protein Family:	50S ribosomal protein
UniProt Gene Name:	RPL12
UniProt Entry Name:	RL12_HUMAN