RNF214 Antibody (PACO17006)
- SKU:
- PACO17006
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RNF214 Antibody (PACO17006) |
| Antibody SKU: | PACO17006 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human RNF214 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 823 cells, PC3 cells, 231 cells, hepg2 cells, Primary antibody: PACO17006(RNF214 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17006(RNF214 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | RNF214 (RING finger protein 214) is a 703 amino acid, protein that contains one RING-type zinc finger and is encoded by a gene that maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Synonyms: | ring finger protein 214 |
| UniProt Protein Function: | RNF214: 2 isoforms of the human protein are produced by alternative splicingProtein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 11q23.3Molecular Function: zinc ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8ND24 |
| NCBI GenInfo Identifier: | 134035028 |
| NCBI Gene ID: | 257160 |
| NCBI Accession: | Q8ND24.2 |
| UniProt Secondary Accession: | Q8ND24,B2RUW0, B4DTD1 |
| UniProt Related Accession: | Q8ND24 |
| Molecular Weight: | |
| NCBI Full Name: | RING finger protein 214 |
| NCBI Synonym Full Names: | ring finger protein 214 |
| NCBI Official Symbol: | RNF214 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | RING finger protein 214 |
| UniProt Protein Name: | RING finger protein 214 |
| UniProt Synonym Protein Names: | |
| Protein Family: | RING finger protein |
| UniProt Gene Name: | RNF214 |
| UniProt Entry Name: | RN214_HUMAN |
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