RNF182 Antibody (PACO38270)
- SKU:
- PACO38270
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RNF182 Antibody (PACO38270) |
| Antibody SKU: | PACO38270 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human E3 ubiquitin-protein ligase RNF182 protein (1-160AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of A431 cells using PACO38270 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO38270 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO38270 at dilution of 1:100. |
| Background: | E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway. |
| Synonyms: | E3 ubiquitin-protein ligase RNF182 (EC 2.3.2.27) (RING finger protein 182) (RING-type E3 ubiquitin transferase RNF182), RNF182 |
| UniProt Protein Function: | RNF182: E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.Protein type: Ubiquitin ligase; EC 6.3.2.-; Ligase; EC 6.3.2.19; Membrane protein, integral; Membrane protein, multi-pass; Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 6p23Cellular Component: cytoplasm; integral to membraneMolecular Function: ligase activity; protein binding; ubiquitin-protein ligase activity; zinc ion bindingBiological Process: protein ubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N6D2 |
| NCBI GenInfo Identifier: | 74751050 |
| NCBI Gene ID: | 221687 |
| NCBI Accession: | Q8N6D2.1 |
| UniProt Secondary Accession: | Q8N6D2,Q8NBG3, B2RDG2 |
| UniProt Related Accession: | Q8N6D2 |
| Molecular Weight: | 27,402 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase RNF182 |
| NCBI Synonym Full Names: | ring finger protein 182 |
| NCBI Official Symbol: | RNF182 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | E3 ubiquitin-protein ligase RNF182 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase RNF182 |
| UniProt Synonym Protein Names: | RING finger protein 182 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | RNF182 |
| UniProt Entry Name: | RN182_HUMAN |
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