RNF148 Antibody (PACO20354)
- SKU:
- PACO20354
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RNF148 Antibody (PACO20354) |
| Antibody SKU: | PACO20354 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human RNF148 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20354(RNF148 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20354(RNF148 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | RNF148 (RING finger protein 148) is a 305 amino acid, single-pass membrane protein that contains one PA (protease associated) domain and a single RING-type zinc finger. RNF148 is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. |
| Synonyms: | ring finger protein 148 |
| UniProt Protein Function: | RNF148: Protein type: Membrane protein, integral; Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 7q31.33Cellular Component: integral to membraneMolecular Function: zinc ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N7C7 |
| NCBI GenInfo Identifier: | 269849640 |
| NCBI Gene ID: | 378925 |
| NCBI Accession: | Q8N7C7.2 |
| UniProt Secondary Accession: | Q8N7C7,Q8N308, A4D0X4 |
| UniProt Related Accession: | Q8N7C7 |
| Molecular Weight: | 34,397 Da |
| NCBI Full Name: | RING finger protein 148 |
| NCBI Synonym Full Names: | ring finger protein 148 |
| NCBI Official Symbol: | RNF148 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | RING finger protein 148 |
| UniProt Protein Name: | RING finger protein 148 |
| UniProt Synonym Protein Names: | |
| Protein Family: | RING finger protein |
| UniProt Gene Name: | RNF148 |
| UniProt Entry Name: | RN148_HUMAN |
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