RNF139 Polyclonal Antibody
- SKU:
- CAB10637
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | RNF139 Polyclonal Antibody |
| Product Code: | CAB10637 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-664 of human RNF139 (NP_009149.2). |
| Sequence: | LQAKN GWKTF MNRRT AVKKI NSLPE IKGSR LQEIN DVCAI CYHEF TTSAR ITPCN HYFHA LCLRK WLYIQ DTCPM CHQKV YIEDD IKDNS NVSNN NGFIP PNETP EEAVR EAAAE SDREL NEDDS TDCDD DVQRE RNGVI QHTGA AAEEF NDDTD |
| Synonyms: | RCA1, TRC8, HRCA1 |
| Calculated MW: | 76kDa |
| Observed MW: | Refer to figures |
Related Products
Doublecortin Polyclonal Antibody
OverviewProduct Name:Doublecortin Polyclonal AntibodyProduct Code:CAB0149Reactivity:Human, MouseApplications:Western blotting, Im
TULP1 Polyclonal Antibody
OverviewProduct Name:TULP1 Polyclonal AntibodyProduct Code:CAB10659Reactivity:HumanApplications:Western blotting
RHBDD1 Polyclonal Antibody
RHBDD1 Polyclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!
ZNF624 Polyclonal Antibody
OverviewProduct Name:ZNF624 Polyclonal AntibodyProduct Code:CAB14916Reactivity:Mouse, RatApplications:Western blotting<
NRTN Polyclonal Antibody
NRTN Polyclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!