RIPPLY2 Antibody (PACO60108)
- SKU:
- PACO60108
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RIPPLY2 Antibody (PACO60108) |
| Antibody SKU: | PACO60108 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein ripply2 protein (1-76AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO60108 diluted at 1:200 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity). |
| Synonyms: | Protein ripply2, RIPPLY2, C6orf159 |
| UniProt Protein Function: | RIPPLY2: Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites. Belongs to the ripply family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6q14.2Cellular Component: nucleusBiological Process: ossification; Notch signaling pathway; somitogenesis; regulation of gene expression; determination of left/right symmetry; somite rostral/caudal axis specification |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5TAB7 |
| NCBI GenInfo Identifier: | 58000465 |
| NCBI Gene ID: | 134701 |
| NCBI Accession: | NP_001009994.1 |
| UniProt Secondary Accession: | Q5TAB7,Q5TAB6 |
| UniProt Related Accession: | Q5TAB7 |
| Molecular Weight: | 8,115 Da |
| NCBI Full Name: | protein ripply2 |
| NCBI Synonym Full Names: | ripply transcriptional repressor 2 |
| NCBI Official Symbol: | RIPPLY2 |
| NCBI Official Synonym Symbols: | C6orf159; dJ237I15.1 |
| NCBI Protein Information: | protein ripply2 |
| UniProt Protein Name: | Protein ripply2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein |
| UniProt Gene Name: | RIPPLY2 |
| UniProt Entry Name: | RIPP2_HUMAN |
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