RING1B/RNF2 Monoclonal Antibody
- SKU:
- CAB24830
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | RING1B/RNF2 Monoclonal Antibody |
| Product Code: | CAB24830 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59707 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:6000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, 293T, NIH/3T3, Mouse testis |
| Cellular Location: | Chromosome, Nucleus |
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RING1B/RNF2 (NP_009143.1). |
| Sequence: | MSQAV QTNGT QPLSK TWELS LYELQ RTPQE AITDG LEIVV SPRSL HSELM CPICL DMLKN TMTTK ECLHR FCADC IITAL RSGNK ECPTC RKKLV SKRSL RPDPN FDALI SKIYP SRDEY EAHQE RVLAR INKHN NQQAL SHSIE EGLKI QAMNR LQRGK KQQIE NGSGA EDNGD SSHCS NASTH SNQEA GPSNK RTKTS DDSGL ELDNN NAAMA IDPVM DGASE IELVF RPHPT LMEKD DSAQT RYIKT SGNAT VDHLS KYLAV RLALE ELRSK GESNQ MNLDT ASEKQ YTIYI ATASG QFTVL NGSFS LELVS EKYWK VNKPM ELYYA PTKEH K |
| Synonyms: | BAP1, DING, BAP-1, HIPI3, RING2, LUSYAM, RING1B |
| Calculated MW: | 38kDa |
| Observed MW: | 41kDa |
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