RIN3 Antibody (PACO58869)
- SKU:
- PACO58869
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RIN3 Antibody (PACO58869) |
| Antibody SKU: | PACO58869 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ras and Rab interactor 3 protein (245-465AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO58869 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. |
| Synonyms: | Ras and Rab interactor 3 (Ras interaction/interference protein 3), RIN3 |
| UniProt Protein Function: | Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. |
| UniProt Protein Details: | |
| NCBI Summary: | Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| UniProt Code: | Q8TB24 |
| NCBI GenInfo Identifier: | 987437828 |
| NCBI Gene ID: | 79890 |
| NCBI Accession: | NP_001306916.1 |
| UniProt Secondary Accession: | Q8TB24,Q76LB3, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1 |
| UniProt Related Accession: | Q8TB24 |
| Molecular Weight: | 107 KD |
| NCBI Full Name: | ras and Rab interactor 3 isoform 2 |
| NCBI Synonym Full Names: | Ras and Rab interactor 3 |
| NCBI Official Symbol: | RIN3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ras and Rab interactor 3 |
| UniProt Protein Name: | Ras and Rab interactor 3 |
| UniProt Synonym Protein Names: | Ras interaction/interference protein 3 |
| Protein Family: | Ras and Rab interactor |
| UniProt Gene Name: | RIN3 |
| UniProt Entry Name: |
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