Anti-RIN3 Antibody (PACO21905)

Antibody Name:	RIN3 Antibody (PACO21905)
Antibody SKU:	PACO21905
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human RIN3.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot analysis of extracts from HUVEC cells and K562 cells, using RIN3 antibody.

Background:	Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. Ota T., Nat. Genet. 36:40-45(2004).
Synonyms:	Ras and Rab interactor 3; Ras interaction/interference protein 3; RIN3;

UniProt Protein Function:	Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
UniProt Protein Details:
NCBI Summary:	Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt Code:	Q8TB24
NCBI GenInfo Identifier:	987437828
NCBI Gene ID:	79890
NCBI Accession:	NP_001306916.1
UniProt Secondary Accession:	Q8TB24,Q76LB3, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1
UniProt Related Accession:	Q8TB24
Molecular Weight:	107 KD
NCBI Full Name:	ras and Rab interactor 3 isoform 2
NCBI Synonym Full Names:	Ras and Rab interactor 3
NCBI Official Symbol:	RIN3
NCBI Official Synonym Symbols:
NCBI Protein Information:	ras and Rab interactor 3
UniProt Protein Name:	Ras and Rab interactor 3
UniProt Synonym Protein Names:	Ras interaction/interference protein 3
Protein Family:	Ras and Rab interactor
UniProt Gene Name:	RIN3
UniProt Entry Name: