Rig-I/DDX58 Polyclonal Antibody
- SKU:
- CAB21421
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Rig-I/DDX58 Polyclonal Antibody |
| Product Code: | CAB21421 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, HepG2, MCF7 |
| Cellular Location: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 825-925 of human Rig-I/DDX58. (NP_055129.2). |
| Sequence: | VIEEC HYTVL GDAFK ECFVS RPHPK PKQFS SFEKR AKIFC ARQNC SHDWG IHVKY KTFEI PVIKI ESFVV EDIAT GVQTL YSKWK DFHFE KIPFD PAEMS K |
| Synonyms: | RIG1, DDX58, RIG-I, RLR-1, SGMRT2 |
| Calculated MW: | 107kDa |
| Observed MW: | Refer to figures |
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