Rig-I/DDX58 Monoclonal Antibody (CAB3689)
- SKU:
- CAB3689
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Rig-I/DDX58 Monoclonal Antibody |
| Product Code: | CAB3689 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0824 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | U-87MG, THP-1 |
| Cellular Location: | actin cytoskeleton, cytoplasm, cytosol, ruffle membrane |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
| Immunogen: | A synthesized peptide derived from human Rig-I/DDX58 |
| Sequence: | Email for sequence |
| Synonyms: | RIG1, DDX58, RIG-I, RLR-1, SGMRT2 |
| Calculated MW: | 107kDa |
| Observed MW: | 107kDa |
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