Rig-I/DDX58 Monoclonal Antibody (CAB23179)
- SKU:
- CAB23179
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Rig-I/DDX58 Monoclonal Antibody |
| Product Code: | CAB23179 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54108 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:4000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Rat liver |
| Cellular Location: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 241-455 of human Rig-I/DDX58 (NP_055129.2). |
| Sequence: | FKPRN YQLEL ALPAM KGKNT IICAP TGCGK TFVSL LICEH HLKKF PQGQK GKVVF FANQI PVYEQ QKSVF SKYFE RHGYR VTGIS GATAE NVPVE QIVEN NDIII LTPQI LVNNL KKGTI PSLSI FTLMI FDECH NTSKQ HPYNM IMFNY LDQKL GGSSG PLPQV IGLTA SVGVG DAKNT DEALD YICKL CASLD ASVIA TVKHN LEELE QVVYK |
| Synonyms: | RIG1, DDX58, RIG-I, RLR-1, SGMRT2 |
| Calculated MW: | 107kDa |
| Observed MW: | 107kDa |
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