Description
Antibody Name: | RIC8B Antibody (PACO11842) |
Antibody SKU: | PACO11842 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human RIC8B |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans);RIC8B;FLJ10620;MGC39476;RIC8;hSyn ; |
UniProt Protein Function: | RIC8B: a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. Interacts with GDP-bound G alpha proteins GNAI1, GNAL, GNAS and GNAQ. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma. Belongs to the synembryn family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, misc.; GEFsChromosomal Location of Human Ortholog: 12q23.3Cellular Component: centrosome; cytoplasm; plasma membrane; cell cortex; cytosolMolecular Function: guanyl-nucleotide exchange factor activity; G-protein alpha-subunit binding; GTPase activator activityBiological Process: regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NVN3 |
NCBI GenInfo Identifier: | 119618193 |
NCBI Gene ID: | 55188 |
NCBI Accession: | EAW97787.1 |
UniProt Secondary Accession: | Q9NVN3,Q4G103, Q6ZRN4, Q86WD3, A2RTZ0 |
UniProt Related Accession: | Q9NVN3 |
Molecular Weight: | 28,953 Da |
NCBI Full Name: | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans), isoform CRA_b |
NCBI Synonym Full Names: | RIC8 guanine nucleotide exchange factor B |
NCBI Official Symbol: | RIC8B |
NCBI Official Synonym Symbols: | RIC8; hSyn |
NCBI Protein Information: | synembryn-B; brain synembrin; brain synembryn; resistance to inhibitors of cholinesterase 8 homolog B |
UniProt Protein Name: | Synembryn-B |
UniProt Synonym Protein Names: | Brain synembryn; hSyn; Protein Ric-8B |
Protein Family: | Synembryn |
UniProt Gene Name: | RIC8B |
UniProt Entry Name: | RIC8B_HUMAN |