Rhesus macaque CD47/IAP Recombinant Protein (RPES3834)

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SKU:
RPES3834
Product Type:
Recombinant Protein
Species:
Monkey

Description

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Rhesus macaque CD47/IAP Recombinant Protein

CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

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