Rhesus macaque CD155/NECL5 Recombinant Protein (RPES3726)

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SKU:
RPES3726
Product Type:
Recombinant Protein
Species:
Monkey

Description

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Rhesus macaque CD155/NECL5 Recombinant Protein

Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (?, β, ?, and ?) with identical extracellular domains.

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