RHEBL1 Antibody (PACO39970)
- SKU:
- PACO39970
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RHEBL1 Antibody (PACO39970) |
| Antibody SKU: | PACO39970 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GTPase RhebL1 protein (1-180AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO39970 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human appendix tissue using PACO39970 at dilution of 1:100. |
| Background: | Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. |
| Synonyms: | GTPase RhebL1 (Ras homolog enriched in brain like-1 c) (RhebL1c) (Ras homolog enriched in brain-like protein 1) (Rheb-like protein 1) (Rheb2), RHEBL1 |
| UniProt Protein Function: | RHEBL1: Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. Belongs to the small GTPase superfamily. Rheb family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric, Rheb; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: 12q13.12Cellular Component: cytoplasmMolecular Function: GTP binding; protein bindingBiological Process: activation of NF-kappaB transcription factor; TOR signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TAI7 |
| NCBI GenInfo Identifier: | 74730357 |
| NCBI Gene ID: | 121268 |
| NCBI Accession: | Q8TAI7.1 |
| UniProt Secondary Accession: | Q8TAI7,Q56VH8 |
| UniProt Related Accession: | Q8TAI7 |
| Molecular Weight: | 8,176 Da |
| NCBI Full Name: | GTPase RhebL1 |
| NCBI Synonym Full Names: | Ras homolog enriched in brain like 1 |
| NCBI Official Symbol: | RHEBL1 |
| NCBI Official Synonym Symbols: | RHEBL1c |
| NCBI Protein Information: | GTPase RhebL1 |
| UniProt Protein Name: | GTPase RhebL1 |
| UniProt Synonym Protein Names: | Ras homolog enriched in brain like-1 c; RhebL1c; Ras homolog enriched in brain-like protein 1; Rheb-like protein 1; Rheb2 |
| Protein Family: | GTPase |
| UniProt Gene Name: | RHEBL1 |
| UniProt Entry Name: | REBL1_HUMAN |
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