Description
| Antibody Name: | RGP1 Antibody (PACO38658) |
| Antibody SKU: | PACO38658 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human RAB6A-GEF complex partner protein 2 protein (56-350AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. |
| Synonyms: | RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog), RGP1, KIAA0258 |
| UniProt Protein Function: | RGP1: Belongs to the RGP1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 9p13.3Cellular Component: cytosol; membrane; protein complex; trans-Golgi network membraneMolecular Function: protein binding; Rab GTPase binding; Rab guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; retrograde transport, endosome to Golgi |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q92546 |
| NCBI GenInfo Identifier: | 2495728 |
| NCBI Gene ID: | 9827 |
| NCBI Accession: | Q92546.1 |
| UniProt Secondary Accession: | Q92546,Q5TCV5 |
| UniProt Related Accession: | Q92546 |
| Molecular Weight: | 42,455 Da |
| NCBI Full Name: | RAB6A-GEF complex partner protein 2 |
| NCBI Synonym Full Names: | RGP1 homolog, RAB6A GEF complex partner 1 |
| NCBI Official Symbol: | RGP1 |
| NCBI Official Synonym Symbols: | KIAA0258 |
| NCBI Protein Information: | RAB6A-GEF complex partner protein 2 |
| UniProt Protein Name: | RAB6A-GEF complex partner protein 2 |
| UniProt Synonym Protein Names: | Retrograde Golgi transport protein RGP1 homolog |
| Protein Family: | |
| UniProt Gene Name: | RGP1 |
| UniProt Entry Name: | RGP1_HUMAN |