RERG Antibody (PACO39538)
- SKU:
- PACO39538
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RERG Antibody (PACO39538) |
| Antibody SKU: | PACO39538 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: RERG antibody at 2µg/ml. Lane 1: Mouse thymus tissue. Lane 2: Rat lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 23, 21 kDa. Observed band size: 23 kDa. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO39538 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO39538 at dilution of 1:100. |
| Background: | Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. |
| Synonyms: | Ras-related and estrogen-regulated growth inhibitor, RERG |
| UniProt Protein Function: | RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric; G protein; G protein, monomeric, RasChromosomal Location of Human Ortholog: 12p12.3Cellular Component: membrane; cytosol; nucleusMolecular Function: GTPase activity; GDP binding; GTP binding; estrogen receptor bindingBiological Process: negative regulation of cell proliferation; metabolic process; small GTPase mediated signal transduction; response to hormone stimulus; negative regulation of cell growth |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96A58 |
| NCBI GenInfo Identifier: | 74731090 |
| NCBI Gene ID: | |
| NCBI Accession: | Q96A58.1 |
| UniProt Secondary Accession: | Q96A58 |
| UniProt Related Accession: | Q96A58 |
| Molecular Weight: | |
| NCBI Full Name: | Ras-related and estrogen-regulated growth inhibitor |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Ras-related and estrogen-regulated growth inhibitor |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ras-related and estrogen-regulated growth inhibitor |
| UniProt Gene Name: | RERG |
| UniProt Entry Name: | RERG_HUMAN |
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