Description
Antibody Name: | Ren2 Antibody (PACO33764) |
Antibody SKU: | PACO33764 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Mouse, Human |
Immunogen: | Recombinant Mouse Renin-2 protein (64-351AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: Ren2 antibody at 2µg/ml + MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa . | |
Western Blot Positive WB detected in: Mouse kidney tissue All lanes: Ren2 antibody at 4µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa . |
Background: | Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. |
Synonyms: | Renin-2 (EC 3.4.23.15) (Angiotensinogenase) (Submandibular gland renin) [Cleaved into: Renin-2 heavy chain; Renin-2 light chain], Ren2, Ren-2 |
UniProt Protein Function: | Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P00796 |
NCBI GenInfo Identifier: | 118150650 |
NCBI Gene ID: | 19702 |
NCBI Accession: | NP_112470.2 |
UniProt Secondary Accession: | P00796,P70229, P97955, Q62155 |
UniProt Related Accession: | P00796 |
Molecular Weight: | 35 kDa |
NCBI Full Name: | renin-2 |
NCBI Synonym Full Names: | renin 2 tandem duplication of Ren1 |
NCBI Official Symbol: | Ren2 |
NCBI Official Synonym Symbols: | Ren; Rnr; Rn-2; Ren-2; Ren-B |
NCBI Protein Information: | renin-2 |
UniProt Protein Name: | Renin-2 |
UniProt Synonym Protein Names: | Angiotensinogenase; Submandibular gland renin |
Protein Family: | Renin |
UniProt Gene Name: | Ren2 |
UniProt Entry Name: |