Description
| Antibody Name: | REM1 Antibody (PACO58865) |
| Antibody SKU: | PACO58865 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GTP-binding protein REM 1 protein (2-153AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of HepG2 cells with PACO58865 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling. |
| Synonyms: | GTP-binding protein REM 1 (GTPase-regulating endothelial cell sprouting) (Rad and Gem-like GTP-binding protein 1), REM1, GES REM |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75628 |
| NCBI GenInfo Identifier: | 20070266 |
| NCBI Gene ID: | 28954 |
| NCBI Accession: | NP_054731.2 |
| UniProt Secondary Accession: | O75628 |
| UniProt Related Accession: | O75628 |
| Molecular Weight: | |
| NCBI Full Name: | GTP-binding protein REM 1 |
| NCBI Synonym Full Names: | RRAD and GEM like GTPase 1 |
| NCBI Official Symbol: | REM1 |
| NCBI Official Synonym Symbols: | GES; GD:REM |
| NCBI Protein Information: | GTP-binding protein REM 1 |
| UniProt Protein Name: | GTP-binding protein REM 1 |
| UniProt Synonym Protein Names: | GTPase-regulating endothelial cell sprouting; Rad and Gem-like GTP-binding protein 1 |
| Protein Family: | GTP-binding protein |
| UniProt Gene Name: | REM1 |
| UniProt Entry Name: | REM1_HUMAN |
