Reg3g Antibody (PACO29452)
- SKU:
- PACO29452
- Product Type:
- Antibody
- Reactivity:
- Rat
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Reg3g Antibody (PACO29452) |
| Antibody SKU: | PACO29452 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat, Mouse |
| Immunogen: | Recombinant Rat Regenerating islet-derived protein 3-γ protein (27-174AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Reg3g antibody at 14µg/ml + Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa . |
| Background: | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (By similarity). |
| Synonyms: | Regenerating islet-derived protein 3-γ (REG-3-gamma) (Pancreatitis-associated protein 3) (Regenerating islet-derived protein III-gamma) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-γ 16.5 kDa form; Regenerating islet-derived protein 3-γ 15 kDa form], Reg3g, Pap3 |
| UniProt Protein Function: | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P42854 |
| NCBI GenInfo Identifier: | 27465527 |
| NCBI Gene ID: | 24620 |
| NCBI Accession: | NP_775120.1 |
| UniProt Secondary Accession: | P42854 |
| UniProt Related Accession: | P42854 |
| Molecular Weight: | 18.3 kDa |
| NCBI Full Name: | regenerating islet-derived protein 3-gamma |
| NCBI Synonym Full Names: | regenerating family member 3 gamma |
| NCBI Official Symbol: | Reg3g |
| NCBI Official Synonym Symbols: | Pap3; PAPIII |
| NCBI Protein Information: | regenerating islet-derived protein 3-gamma |
| UniProt Protein Name: | Regenerating islet-derived protein 3-gamma |
| UniProt Synonym Protein Names: | Pancreatitis-associated protein 3; Regenerating islet-derived protein III-gamma; Reg III-gamma |
| Protein Family: | Regenerating islet-derived protein |
| UniProt Gene Name: | Reg3g |
| UniProt Entry Name: | REG3G_RAT |
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