Antibody Name:	REG3G Antibody (PACO16680)
Antibody SKU:	PACO16680
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:	Human, Mouse
Immunogen:	Fusion protein of human REG3G

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse pancreas tissue, Primary antibody: PACO16680(REG3G Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16680(REG3G Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).

Background:	This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antibacterial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
Synonyms:	regenerating islet-derived 3 gamma

UniProt Protein Function:	REG3G: Might be a stress protein involved in the control of bacterial proliferation.
UniProt Protein Details:	Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2p12 Cellular Component: cytoplasm; extracellular region Molecular Function:peptidoglycan binding Biological Process: acute-phase response; antimicrobial humoral response; cytolysis in other organism; defense response to Gram-positive bacterium; MyD88-dependent toll-like receptor signaling pathway; negative regulation of keratinocyte differentiation
NCBI Summary:	This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014]
UniProt Code:	Q6UW15
NCBI GenInfo Identifier:	56699413
NCBI Gene ID:	130120
NCBI Accession:	NP_001008388.1
UniProt Secondary Accession:	Q6UW15,Q3SYE4, Q3SYE6, Q6FH18, A8K980, D6W5J6,
UniProt Related Accession:	Q6UW15
Molecular Weight:
NCBI Full Name:	regenerating islet-derived protein 3-gamma isoform 1 preproprotein
NCBI Synonym Full Names:	regenerating family member 3 gamma
NCBI Official Symbol:	REG3G
NCBI Official Synonym Symbols:	PAP1B; PAPIB; PAP IB; PAP-1B; UNQ429; LPPM429; REG III; REG-III
NCBI Protein Information:	regenerating islet-derived protein 3-gamma
UniProt Protein Name:	Regenerating islet-derived protein 3-gamma
UniProt Synonym Protein Names:	Pancreatitis-associated protein 1B; PAP-1B
Protein Family:	Regenerating islet-derived protein
UniProt Gene Name:	REG3G