Description
| Antibody Name: | Reg3b Antibody (PACO34350) |
| Antibody SKU: | PACO34350 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Regenerating islet-derived protein 3-β protein (27-175AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). |
| Synonyms: | Regenerating islet-derived protein 3-β (REG-3-beta) (Pancreatitis-associated protein 1) (Peptide 23) (REG-2) (Regenerating islet-derived protein III-beta) (Reg III-beta) [Cleaved into: Regenerating islet-derived protein 3-β 16.5 kDa form; Regenerating islet-derived protein 3-β 15 kDa form], Reg3b, Pap Pap1 Reg2 |
| UniProt Protein Function: | Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. |
| NCBI Summary: | lectin-related secretory protein; may be involved in stress response to control bacterial proliferation during acute pancreatitis [RGD, Feb 2006] |
| UniProt Code: | P25031 |
| NCBI GenInfo Identifier: | 16757982 |
| NCBI Gene ID: | 24618 |
| NCBI Accession: | NP_445741.1 |
| UniProt Secondary Accession: | P25031,Q64102, Q64231, |
| UniProt Related Accession: | P25031 |
| Molecular Weight: | 20.6 kDa |
| NCBI Full Name: | regenerating islet-derived protein 3-beta |
| NCBI Synonym Full Names: | regenerating islet-derived 3 beta |
| NCBI Official Symbol: | Reg3b |
| NCBI Official Synonym Symbols: | Pap; Pap1 |
| NCBI Protein Information: | regenerating islet-derived protein 3-beta |
| UniProt Protein Name: | Regenerating islet-derived protein 3-beta |
| UniProt Synonym Protein Names: | Pancreatitis-associated protein 1; Peptide 23; REG-2; Regenerating islet-derived protein III-beta; Reg III-beta |
| Protein Family: | Regenerating islet-derived protein |
| UniProt Gene Name: | Reg3b |
| UniProt Entry Name: | REG3B_RAT |