Description
Background
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Information | Description |
Product Name: | SARS-Cov-2 NP NTD domain (His Tag) |
Size: | 1mg |
SKU: | RPES0022 |
Activity: | |
Synonym: | 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein |
Protein Construction: | SARS-Cov-2 NP NTD domain is produced by our E.coli expression system with a 6His tag at the N-terminus. |
Sequence: | |
Fusion tag: | N-6His |
Accession: | QHD43423.2 |
Species: | Virus |
Expressed Host: | E.coli |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Mol Mass: | 15.9 kDa |
AP Mol Mass: | 16 kDa |
Formulation: | Supplied as a 0.2 uM filtered solution of PBS, 2M Urea, pH 7.4. |
Reconstitution: | Please refer to the printed manual for detailed information. |