Description
Background
ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
Information | Description |
Product Name: | Recombinant Mouse APN Protein (His Tag) |
Size: | 10µg |
SKU: | RPES0038 |
Activity: | |
Synonym: | Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN |
Protein Construction: | Recombinant Mouse Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69Ser966 is expressed with a 6His tag at the C-terminus. |
Sequence: | Lys69Ser966 |
Fusion tag: | C-6His |
Accession: | P97449 |
Species: | Human |
Expressed Host: | Human Cells |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months. |
Mol Mass: | 103.6 kDa |
AP Mol Mass: | 110-130 kDa |
Formulation: | Supplied as a 0.2 uM filtered solution of PBS, pH 7.4. |
Reconstitution: | Please refer to the printed manual for detailed information. |