Recombinant Human/Mouse/Rat GDF-8/Myostatin (RPES6813)

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SKU:
RPES6813
Product Type:
Recombinant Protein
Species:
Human
Species:
Mouse
Species:
Rat

Description

Product Name:Recombinant Human/Mouse/Rat GDF-8/Myostatin
Product Code:RPES6813
Size:10µg
Species:Human/Mouse/Rat
Expression Host:HEK293 Cells
Synonyms:Growth/differentiation factor 8, GDF-8, Myostatin, Mstn, Gdf8
Mol Mass:13.1 kDa
AP Mol Mass:12-15 kDa
Tag:None
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Lys262-Ser375
Accession:O14793
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
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