Description
Product Name: | Recombinant Human Integrin Beta-1/ITGB1 (C-6His) |
Product Code: | RPES6193 |
Size: | 10µg |
Species: | Human |
Expression Host: | HEK293 Cells |
Synonyms: | Integrin Beta-1, Fibronectin Receptor Subunit Beta, VLA-4 Subunit Beta, CD29, ITGB1, FNRB, MDF2, MSK12 |
Mol Mass: | 79.4 kDa |
AP Mol Mass: | 100-130 kDa |
Tag: | C-6His |
Purity: | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
Bio Activity: | Testing in progress |
Sequence: | Gln21-Asp728 |
Accession: | P05556 |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution: | Please refer to the printed manual for detailed information. |
Background: | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |