Name: Recombinant Human IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-6His-Avi) Biotinylated
SKU: RPES6268
Availability: OutOfStock

Recombinant Human IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-6His-Avi) Biotinylated

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SKU:

RPES6268

Product Type:

Recombinant Protein

Species:

Human

Description

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OverviewProduct Name:Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-6His)Product Code:RPES6672Size:10µgSpecies:Mous

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Mol Mass:	27.4 kDa
AP Mol Mass:	35-45 kDa
Tag:	C-6His-Avi
Purity:	> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:	< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:	Testing in progress

Sequence:	Ala27-Asp239
Accession:	P14784
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.