Name: Recombinant Human FGL1 (C-Fc-Avi) Biotinylated
SKU: RPES6207
Availability: OutOfStock

Recombinant Human FGL1 (C-Fc-Avi) Biotinylated

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RPES6207

Description

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Additional Information

Product Type:	Recombinant Protein
Species:	Human

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Mol Mass:	62.7 kDa
AP Mol Mass:	60 kDa
Tag:	C-Fc-Avi
Purity:	> 90 % as determined by reducing SDS-PAGE.
Endotoxin Level:	< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:	Immobilized Mouse LAG-3-His at 2μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi. The ED50 of Human FGL1-Avi(CY19) is 0.08ug/ml.

Sequence:	Leu23-Ile312
Accession:	Q08830
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manu
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .