Recombinant Human FGL1 (C-Fc)
- SKU:
- RPES6206
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
| Product Name: | Recombinant Human FGL1 (C-Fc) |
| Product Code: | RPES6206 |
| Size: | 10µg |
| Species: | Human |
| Expression Host: | HEK293 Cells |
| Synonyms: | Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1 |
| Mol Mass: | 60.9 kDa |
| AP Mol Mass: | 55-65 kDa |
| Tag: | C-Fc |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Immobilized Cynomolgus LAG-3-His at 2μg/ml (100 μl/well) can bind Human FGL1-Fc. The ED50 of Human FGL1-Fc is 5. 8 ug/ml. |
| Sequence: | Leu23-Ile312 |
| Accession: | Q08830 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manu |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 . |
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