Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-Fc)

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SKU:
RPES6295
Product Type:
Recombinant Protein
Species:
Human

Description

Product Name:Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-Fc)
Product Code:RPES6295
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:Butyrophilin Subfamily 1 Member A1, BT, BTN1A1, BTN
Mol Mass:50.8 kDa
AP Mol Mass:60-80 kDa
Tag:C-Fc
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Ala27-Arg242
Accession:Q13410
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
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