Human APN Recombinant Protein (RPES0037)

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SKU:
RPES0037
Product Type:
Recombinant Protein
Species:
Human

Description

Background

ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.

Information Description
Product Name:
Recombinant Human APN Protein (His Tag)
Size:

10µg

SKU:

RPES0037
Activity:
Synonym:
Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; PEPN; PEPNhAPN
Protein Construction:
Recombinant Human Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69­Lys967 is expressed with a 6His tag at the C-terminus.
Sequence:
Lys69­Lys967
Fusion tag:
C-6His
Accession:
P15144
Species:
Human
Expressed Host:
Human Cells
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Endotoxin:
< 1.0 EU per µg as determined by the LAL method.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.
Mol Mass:
103.5 kDa
AP Mol Mass:
110-130 kDa
Formulation:
Supplied as a 0.2 uM filtered solution of PBS, pH 7.4.
Reconstitution:
Please refer to the printed manual for detailed information.
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