Recombinant Cynomolgus FGL1 (C-6His)

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SKU:
RPES6767
Product Type:
Recombinant Protein
Species:
Monkey

Description

Product Name:Recombinant Cynomolgus FGL1 (C-6His)
Product Code:RPES6767
Size:10µg
Species:Cynomolgus macaques
Expression Host:HEK293 Cells
Synonyms:Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27
Mol Mass:34.8 kDa
AP Mol Mass:35 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Loaded Cynomolgus LAG-3-Fc on Protein A Biosensor, can bind Cynomolgus FGL1-His with an affinity constant of 28.6nM as determined in BLI assay.
Sequence:Leu23-Ile312
Accession:A0A2K5X990
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 300mM NaCl, 50% Glycerol, 0.05% Tween 80, pH 8.5 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the s
Reconstitution:Not Applicable
Background:Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
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