Description
Product Name: | Recombinant Cynomolgus CD3D&CD3E Heterodimer (C-Fc-Flag&C-Fc-6His) |
Product Code: | RPES6796 |
Size: | 10µg |
Species: | Cynomolgus macaques |
Expression Host: | HEK293 Cells |
Synonyms: | CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon |
Mol Mass: | 37&38.3 kDa |
AP Mol Mass: | 40-60 kDa |
Tag: | C-Fc-Flag&C-Fc-6His |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
Bio Activity: | Testing in progress |
Sequence: | Phe22-Ala105&Gln22-Asp117 |
Accession: | Q95LI8&Q95LI5 |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution: | Please refer to the printed manual for detailed information. |
Background: | T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |