Description
Product Name: | RCN1 Polyclonal Antibody |
Product Code: | CAB21590 |
Reactivity: | Human |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Endoplasmic reticulum lumen |
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-331 of human RCN1 (NP_002892.1). |
Sequence: | KPTVR KERVV RPDSE LGERP PEDNQ SFQYD HEAFL GKEDS KTFDQ LTPDE SKERL GKIVD RIDND GDGFV TTEEL KTWIK RVQKR YIFDN VAKVW KDYDR DKDDK ISWEE YKQAT YGYYL GNPAE FHDSS DHHTF KKMLP RDERR FKAAD LNGDL TATRE EFTAF LHPEE FEHMK EIVVL ETLED IDKNG DGFVD QDEYI ADMFS HEENG PEPDW VLSER EQFNE FRDLN KDGKL DKDEI RHWIL PQDYD HAQAE ARHLV YESDK NKDEK LTKEE ILENW NMFVG SQATN YGEDL TKNHD EL |
Synonyms: | RCN, RCAL, PIG20, HEL-S-84 |
Calculated MW: | 39kDa |
Observed MW: | Refer to figures |