Description
Product Name: | RBBP5 Monoclonal Antibody |
Product Code: | CAB23124 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59746 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | K-562, HeLa, Mouse brain, Mouse testis, Mouse stomach, Rat thymus, Rat testis |
Cellular Location: | Nucleus |
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 319-538 of human RBBP5(NP_005048.2). |
Sequence: | SIWAQ NQVEN WSAFA PDFKE LDENV EYEER ESEFD IEDED KSEPE QTGAD AAEDE EVDVT SVDPI AAFCS SDEEL EDSKA LLYLP IAPEV EDPEE NPYGP PPDAV QTSLM DEGAS SEKKR QSSAD GSQPP KKKPK TTNIE LQGVP NDEVH PLLGV KGDGK SKKKQ AGRPK GSKGK EKDSP FKPKL YKGDR GLPLE GSAKG KVQAE LSQPL TAGGA ISELL |
Synonyms: | RBQ3, SWD1 |
Calculated MW: | 59kDa |
Observed MW: | 70kDa |