Rat Semaphorin 4D/SEMA4D/ Recombinant Protein (RPES4482)
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- SKU:
- RPES4482
- Product Type:
- Recombinant Protein
- Species:
- Rat
Description
system_update_altDatasheet
Rat Semaphorin 4D/SEMA4D/ Recombinant Protein
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
| Product Name: | Rat Semaphorin 4D/SEMA4D/ Recombinant Protein (RPES4482) |
| Product Code: | RPES4482 |
| Size: | 50µg |
| Species: | Rat |
| Expressed Host: | HEK293 Cells |
| Synonyms: | SEMA4D |
| Accession: | NP_001164034.1 |
| Sequence: | Met1-Met712 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method |
| Protein Construction: | A DNA sequence encoding the rat SEMA4D (Met1-Met712) was expressed, fused with a polyhistidine tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 77.8 kDa |
| AP Mol Mass: | 96 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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