Chemokines Recombinant Proteins

Rat MIP 1b Recombinant Protein (RPPB1219)

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SKU:
RPPB1219
Product Type:
Recombinant Protein
Species:
Rat
Uniprot:
P50230
Research Area:
Chemokines

Description

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Product Name:Rat MIP 1b Recombinant Protein
Product Code:RPPB1219
Size:20µg
Species:Rat
Target:MIP 1b
Synonyms:C-C motif chemokine 4, Macrophage inflammatory protein 1-beta, MIP-1-beta, Small-inducible cytokine A4, Ccl4, Mip1b, Scya4.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Filtered (0.2�m) and lyophilized from a concentrated (1mg/ml) solution in 30% Acetonitrile and 0.1% TFA.
Solubility:It is recommended to reconstitute the lyophilized Mouse MIP-1b in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized Mouse MIP-1b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse CCL4 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:APIGSDPPTS CCFSYTSRKI HRNFVMDYYE TSSLCSQPAV VFLTKKGRQI CADPSEPWVN EYVNDLELN
Biological Activity:Determined by its ability to chemoattract human monocytes using a concentration range of 0.01-1.0 �g/ml.

Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines.

MIP-1b Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 69 amino acids and having a molecular mass of 7.8 kDa. The MIP-1b is purified by proprietary chromatographic techniques.

UniProt Protein Function:Monokine with inflammatory and chemokinetic properties.
NCBI Summary:a cytokine that is up-regulated during the inflammatory response; may be involved in intrapulmonary recruitment of neutrophils [RGD, Feb 2006]
UniProt Code:P50230
NCBI GenInfo Identifier:1709025
NCBI Gene ID:116637
NCBI Accession:P50230.1
UniProt Secondary Accession:P50230,A1EC89,
UniProt Related Accession:P50230
Molecular Weight:10,234 Da
NCBI Full Name:C-C motif chemokine 4
NCBI Synonym Full Names:chemokine (C-C motif) ligand 4
NCBI Official Symbol:Ccl4��
NCBI Official Synonym Symbols:Scya4; Mip1-b��
NCBI Protein Information:C-C motif chemokine 4; MIP-1-beta; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta
UniProt Protein Name:C-C motif chemokine 4
UniProt Synonym Protein Names:Macrophage inflammatory protein 1-beta; MIP-1-beta; Small-inducible cytokine A4
Protein Family:C-C motif chemokine
UniProt Gene Name:Ccl4��
UniProt Entry Name:CCL4_RAT
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