Growth Factors & Cytokines Recombinant Proteins
Rat M-CSF/CSF1 Recombinant Protein (RPES0456)
- SKU:
- RPES0456
- Product Type:
- Recombinant Protein
- Species:
- Rat
- Research Area:
- Growth Factors & Cytokines
Description
Rat M-CSF/CSF1 Recombinant Protein
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
| Product Name: | Rat M-CSF/CSF1 Recombinant Protein (RPES0456) |
| Product Code: | RPES0456 |
| Size: | 10µg |
| Species: | Rat |
| Expressed Host: | Human cells |
| Synonyms: | Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1 |
| Accession: | Q8JZQ0 |
| Sequence: | Gln33-Arg254 |
| Endotoxin: | <1.0 EU per µg as determined by LAL test. |
| Protein Construction: | Recombinant Rat Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Gln33-Arg254 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 25.2 kDa |
| AP Mol Mass: | 25.2 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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