Rat Interleukin-2/IL-2 Recombinant Protein (His Tag)

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SKU:
RPES6140
Product Type:
Recombinant Protein
Species:
Rat

Description

Product Name:Rat Interleukin-2/IL-2 Recombinant Protein (His Tag)
Product Code:RPES6140
Size:20µg
Species:Rat
Expression Host:HEK293 Cells
Synonyms:Aldesleukin, IL 2, IL-2, IL2, IL2, Interleukin 2, Interleukin-2, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T Cell Growth Factor, T-cell growth factor, TCGF
Mol Mass:14.74 kDa
AP Mol Mass:16 kDa
Tag:C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Ala 21-Gln 155
Accession:P17108
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
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