Growth Factors & Cytokines Recombinant Proteins
Rat FGF-18 Recombinant Protein (RPPB0236)
- SKU:
- RPPB0236
- Product Type:
- Recombinant Protein
- Species:
- Rat
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Rat FGF-18 Recombinant Protein |
| Product Code: | RPPB0236 |
| Size: | 25µg |
| Species: | Rat |
| Target: | FGF-18 |
| Synonyms: | Fibroblast growth factor 18, FGF-18, zFGF5, Fgf18, D130055P09Rik. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a 0.2um filtered concentrated solution in PBS, pH 7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized FGF 18 in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized FGF 18 Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF 18 Rat should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE and HPLC analyses. |
| Amino Acid Sequence: | EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLL VETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYS GWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQTELQK PFKYTTVTKR SRRIRPTHPG |
| Biological Activity: | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is�< 0.5ng/ml, corresponding to a specific activity of�> 2.0�1,000,000 units/mg. |
Fibroblast growth factor 18 (FGF18) is a member of the large FGF family which has at least 23 members. FGF18 is a growth factor with a core 120 amino acid FGF domain which allows for a common tertiary structure. FGFs are expressed in the course of the embryonic development and in restricted adult tissues. FGF-18 is an indispensable regulator of long bone and calvarial development. FGF-18 signals via FGFR 1c, 2c, 3c, and 4.
FGF18 Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 21.0kDa.The�FGF 18 Rat is purified by proprietary chromatographic techniques.
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