Neurotrophins Recombinant Proteins

Rat CNTFR Recombinant Protein (RPPB0135)

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SKU:
RPPB0135
Product Type:
Recombinant Protein
Species:
Rat
Uniprot:
Q08406
Research Area:
Neurotrophins

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Rat CNTFR Recombinant Protein
Product Code:RPPB0135
Size:20µg
Species:Rat
Target:CNTFR
Synonyms:Ciliaryneurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless clear solution.
Formulation:CNTFR protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:QKHSPQEAPH VQYERLGTDV TLPCGTASWD AAVTWRVNGT DLAPDLLNGSQLILRSLELG HSGLYACFHR DSWHLRHQVL LHVGLPPREP VLSCRSNTYP KGFYCSWHLS APTYIPNTFNVTVLHGSKMM VCEKDPALKN RCHIRYMHLF STIKYKVSIS VSNALGHNTT AITFDEFTIVKPDPPENVVA RPVPSNPRRLEVTWQTPSTW PDPESFPLKF FLRYRPLILD QWQHVELSNG TAHTITDAYA GKEYIIQVAA KDNEIGTWSD WSVAAHATPWTEEPRHLTTE AQAPETTTST TSSLAPPPTT KICDPGELSS LEHHHHHH
UniProt Code:Q08406

Ciliary Neurotrophic Factor Receptor, also known as CNTFR is a member of the type I cytokine receptor family. CNTFR binds to CNTF.The alpha subunit provides the receptor specificity.Sole nucleotide polymorphisms in CNTFR has been associated with variations in muscle strength, in addition to early onset of eating disorders.

CNTFR Rat Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 328 amino acids (23-342a.a) and having a molecular mass of 36.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).CNTFR is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

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